What cancers Are You at Risk for with Lynch syndrome?
Lynch syndrome is an inherited condition that increases your risk of colon cancer, endometrial cancer and several other cancers. Lynch syndrome has historically been known as hereditary nonpolyposis colorectal cancer (HNPCC).
Is Lynch syndrome the same as HNPCC?
Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC), is the most common cause of hereditary colorectal (colon) cancer.
How common is HNPCC?
Colorectal cancer is the third most common form of cancer in the United States, with approximately 130,000 cases diagnosed each year. It is also the second leading cause of cancer deaths in the United States.
How is HNPCC treated?
Several different operations are currently available for the treatment of hereditary nonpolyposis colorectal cancer (HNPCC)….The 3 most commonly performed operations are as follows:
- Subtotal colectomy with ileorectal anastomosis.
- Total colectomy with ileoanal pull-through (pouch procedure)
- Total colectomy with ileostomy.
How is HNPCC diagnosed?
There are two screening examinations for colorectal cancer and HNPCC:
- Sigmoidoscopy—a diagnostic procedure that allows the doctor to examine the lower one-third of the large intestine.
- Colonoscopy—a diagnostic procedure that allows the physician to examine the entire length of the large intestine.
Can you survive Lynch syndrome?
Currently, there is no cure for Lynch syndrome. Patients with Lynch syndrome should undergo lifelong cancer screening beginning in adulthood.
How is HNPCC inherited?
How Is HNPCC Inherited? HNPCC is an autosomal dominant condition. This means that people with HNPCC have a 50% chance of passing the HNPCC gene mutation (change) to each of their children. The gene mutation can be passed on even if the parent has had surgery to remove his or her own colon.
What are symptoms of HNPCC?
|Medical Terms||Other Names|
|Flexion contracture||Flexed joint that cannot be straightened|
|Gait disturbance||Abnormal gait Abnormal walk Impaired gait [ more ]|
|Hallucinations||Hallucination Sensory hallucination [ more ]|
|Hemiplegia/hemiparesis||Paralysis or weakness of one side of body|
Is HNPCC curable?
Can you get life insurance with Lynch syndrome?
The GINA act does not prevent insurance companies from using Lynch Syndrome in their underwriting for life insurance. This may prevent a person from obtaining reasonably priced life insurance once the diagnosis is made.
Should I get a hysterectomy if I have Lynch syndrome?
Conclusions: These findings suggest that prophylactic hysterectomy with bilateral salpingo-oophorectomy is an effective strategy for preventing endometrial and ovarian cancer in women with the Lynch syndrome.