Is MIBG a PET scan?
Although the MIBG scan is the test of choice for detection of a phaeochromocytoma and neuroblastoma, at times poorly differentiated tumours can be MIBG-negative. In this case, detection is better achieved with positron-emission tomography (PET) scans.
Which of the following drugs does not interfere with the uptake and retention of MIBG?
Clonidine produced a modest inhibition of retention and yohimbine had no effect. Labetalol, phenoxybenzamine, guanethidine, and propranolol reduced uptake of [125I]MIBG by neuroblastoma cells in culture.
What does a MIBG scan show?
MIBG is a nuclear scan test that uses injected radioactive material (radioisotope) and a special scanner to locate or confirm the presence of pheochromocytoma and neuroblastoma, which are tumors of specific types of nervous tissue.
What does MIBG stand for?
MIBG stands for meta-iodobenzylguanidine — a molecule that is actively absorbed by neuroblastoma cells. When radioactive iodine is attached to MIBG, the combination is referred to as I131-MIBG.
Is MIBG scan safe?
What are the risks of an MIBG scan? Apart from the possibility of an increase in blood pressure, which is a relatively rare side-effect, there are no significant risks. Any increase in blood pressure usually resolves within 48 hours after the injection and rarely requires treatment.
What age is neuroblastoma diagnosed?
The average age of children when they are diagnosed is about 1 to 2 years. Rarely, neuroblastoma is detected by ultrasound even before birth. About 9 out of 10 neuroblastomas are diagnosed by age 5. It is rare in people over the age of 10 years.